Non-invasive neuromodulation

rTMS –
targeted where the network is out of rhythm

For most people with depression, what has been treated so far is the chemistry of the brain, never the brain itself. rTMS changes that: magnetic pulses reach the prefrontal cortex, which is measurably underactive in depression, as an outpatient and without anaesthesia, and it is recommended in the German S3 guideline. Whether it is the right starting point for you is settled by the assessment before the first session.

What it is

rTMS (repetitive transcranial magnetic stimulation) is a non-invasive neuromodulation procedure: a pulsed magnetic field passes through the skull and activates or dampens nerve cells, usually in the prefrontal cortex. In treatment-resistant depression, rTMS is recommended in clinical guidelines; treatment runs as outpatient session series, without anaesthesia and without adding medication.

rTMS has been approved for depression in the United States since 2008 and is among the most thoroughly studied neuromodulation methods. Brief magnetic pulses change the activity of a targeted brain region; depending on the frequency, the region is activated or dampened. It has nothing in common with electroconvulsive therapy: no seizure, no anaesthesia, and you stay awake and responsive for the whole session.

Our device: MagVenture X100

How it works

The mechanism, made clear

On our MagVenture X100 we position a figure-8 coil on the articulated support arm over the target area; in depression that is usually the left dorsolateral prefrontal cortex. The rapidly changing magnetic field induces small currents in the tissue beneath, and the nerve cells fire. Repeated over weeks, the activity and connectivity of the region re-tune; that is neuroplasticity, the same capacity the brain uses whenever it learns. Where the coil sits and which frequency we use follows from the assessment, with a qEEG where the question calls for it.

For us, rTMS is above all a way to regulate functional balance without adding medication — with the aim of restoring function and quality of life.

Protocol · example
10 Hz·3,000 pulses·20 min
Target: left DLPFC
What a session is like

What to expect

You sit in a treatment chair with the coil resting against the outside of your head. A classic session lasts 20 to 40 minutes depending on the protocol, a theta-burst protocol only a few minutes. You hear a rhythmic tapping and feel it on the scalp; sometimes the forehead muscles twitch along. The most common side effect is a temporary headache or a tender scalp; seizures are very rare, which is why we screen for contraindications such as metal in the head beforehand. Afterwards your day carries on as normal. What we observe in the clinic: in a subset of people who respond hesitantly to rTMS alone, the course changes once the thyroid, sleep or a source of inflammation is treated alongside. Studies describe what works on average across many people; the person in front of us is not an average. So we combine methods the way the assessment suggests, as an informed treatment attempt, and what we see feeds into every concept that follows.

What we use it for

rTMS is best evidenced for depression, above all when medication has not helped enough. With growing to solid evidence come obsessive-compulsive disorder, anxiety disorders, chronic pain syndromes and motor rehabilitation after stroke; for depression and neuropathic pain there are guideline recommendations, and beyond those we use rTMS as an individual, informed treatment attempt. With us, rTMS is one building block among several: an underactive prefrontal cortex in someone with an untreated underactive thyroid is a thyroid case first, and lived experience measurably changes the wiring, which is why labs, hormone status and psychological support belong in the same plan as the coil. Treatment is outpatient in Bad Aibling, TMS therapy near Munich, about 50 minutes via the A8.

See all conditions — and what fits you is decided by the assessment, with qEEG where the question calls for it.

The course

What does a rTMS course with us look like?

Step 1 · approx. 30 min

First consultation

Free of charge: we go through your concern, prior treatments, medication and contraindications and tell you whether rTMS is an option for you at all. Book a consultation.

Step 2 · 60 to 90 min

Assessment

Before any stimulation we take stock: history, existing findings, questionnaires, clinical examination and, where needed, labs and imaging. qEEG brain mapping is added when the question calls for it.

Step 3 · 1 session

Target & protocol

We define the target region, the frequency and your stimulation intensity (motor threshold), and decide between a classic 10 Hz series, iTBS or, in suitable cases, the accelerated protocol.

Step 4 · 4 to 6 weeks

Treatment series

Typically 20 to 30 sessions on five days a week: 20 to 40 minutes at 10 Hz, a few minutes with iTBS. The accelerated protocol compresses several sessions a day into about five days.

Step 5 · ongoing

Progress measurement

Questionnaires during the series, then the comparison with your baseline, with a qEEG check where needed. From that we adjust the protocol and plan maintenance sessions if they are needed.

Evidence by indication

Which conditions is rTMS evidenced for?

Evidence grade, typical protocol and context — per indication. Scale: strong · solid · moderate · growing · early. A high grade describes the state of the research, not your individual course.

IndicationEvidence gradeTypical protocolNote
DepressionStrong10 Hz left DLPFC or iTBS · 20–30 sessions over 4–6 weeksBest evidence of all indications; recommended in guidelines when medication has not helped enough.
Treatment-resistant depressionStrongStandard series or accelerated iTBS (SNT-type, approx. 5 days)Primary indication. Response is individual and measured throughout.
OCDSolidDeep TMS / high-frequency over mPFC–ACC or low-frequency over the SMA · 20–30 sessionsMeta-analyses show moderate effects; adjunct to behavioural therapy.
Chronic (neuropathic) painSolidHigh-frequency over the motor cortex (M1) contralateral to the pain · series + maintenanceGuideline recommendation for neuropathic pain; weaker evidence for other pain types.
TinnitusModerate1 Hz over the auditory cortex · 10–20 sessionsEffects small and heterogeneous; case-by-case decision, not a standard.
Long COVID – fatigue & brain fogEarlyHigh-frequency left DLPFC · usually 10–20 sessions (pilot protocols)First small studies; off-label, only after thorough informed consent.
Negative symptoms of schizophreniaModerateHigh-frequency left DLPFC · 15–20 sessionsNetwork meta-analysis with small to moderate effects; adjunct to standard psychiatric care.
Stroke rehabilitation (motor)Solid1 Hz over the unaffected or high-frequency over the affected hemisphere · paired with physiotherapyAdded effect on top of training in meta-analyses; courses vary widely.
Who it is not for

Who should not have rTMS?

We screen for contraindications in the first consultation, before any protocol is planned. rTMS is not suitable — or only after individual medical review — in case of:

  • Ferromagnetic metal in the head (e.g. vascular clips, shrapnel, cochlear implant): absolute contraindication
  • Implanted electronic devices (pacemaker, defibrillator, neurostimulator, drug pump): only after individual review
  • Epilepsy or a history of seizures: increased risk, strict assessment
  • Pregnancy: case-by-case decision
  • Acute severe physical illness or an unstable cardiovascular situation
  • Medication or substances that lower the seizure threshold, and acute withdrawal: only after review
  • Children and adolescents: only after special medical consideration
Cost

How much does rTMS cost?

We provide rTMS for self-paying and privately insured patients; German statutory insurers so far cover outpatient rTMS only in exceptional cases after an individual application. The price depends on the protocol and the number of sessions, and 20 to 30 sessions is a realistic planning basis. What a single session costs, how series are built and how a reimbursement application works is explained in our article TMS therapy cost & insurance; you leave the first consultation with a concrete cost plan.

Science & Studies

What the research shows

Peer-reviewed work on rTMS (Repetitive Transcranial Magnetic Stimulation) — graded by evidence level. No study proves an individual outcome.

RCT

Effectiveness of theta burst versus high-frequency rTMS in depression (THREE-D): a randomised non-inferiority trial

Lancet· 2018Read study ↗
Meta-analysis

Effects of rTMS of the left dorsolateral prefrontal cortex on symptom domains in neuropsychiatric disorders: a systematic review and cross-diagnostic meta-analysis

Lancet Psychiatry· 2023Read study ↗
Meta-analysis

Recovering from depression with repetitive transcranial magnetic stimulation (rTMS): a systematic review and meta-analysis

Transl Psychiatry· 2020Read study ↗
Meta-analysis

Transcranial Magnetic Stimulation and Transcranial Direct Current Stimulation Across Mental Disorders: A Systematic Review and Dose-Response Meta-Analysis

JAMA Netw Open· 2024Read study ↗
Meta-analysis

Theta burst stimulation for depression: a systematic review and network and pairwise meta-analysis

Mol Psychiatry· 2024Read study ↗
Meta-analysis

A Meta-analysis of Transcranial Magnetic Stimulation in Obsessive-Compulsive Disorder

Biol Psychiatry CNNI· 2023Read study ↗
Meta-analysis

Repetitive Transcranial Magnetic Stimulation for Obsessive-Compulsive Disorder: A Meta-analysis of Randomized, Sham-Controlled Trials

Biol Psychiatry CNNI· 2021Read study ↗
Guideline

Safety and recommendations for TMS use in healthy subjects and patient populations: Expert Guidelines

Clin Neurophysiol· 2021Read study ↗
Guideline

Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): an update (2014–2018)

Clin Neurophysiol· 2020Read study ↗
Meta-analysis

Repetitive transcranial magnetic stimulation for motor recovery after stroke: a systematic review and meta-analysis of randomized controlled trials with low risk of bias

Neuromodulation· 2025Read study ↗
Meta-analysis

Assessment of noninvasive brain stimulation interventions for negative symptoms of schizophrenia: a systematic review and network meta-analysis

JAMA Psychiatry· 2022Read study ↗
Klinische Studie

Effect of repetitive transcranial magnetic stimulation on long coronavirus disease 2019 with fatigue and cognitive dysfunction

Prog Rehabil Med· 2023Read study ↗

More: Science & Studies.

Frequently asked

Questions about rTMS, answered briefly

What is rTMS?
rTMS stands for repetitive transcranial magnetic stimulation: a pulsed magnetic field passes through the skull and activates nerve cells in a targeted way, usually in the prefrontal cortex. The procedure is non-invasive, needs neither anaesthesia nor added medication, and is delivered as outpatient series. Its strongest data are in depression when medication has not helped enough. More: How does rTMS work?
How many rTMS sessions are needed?
Usually 20 to 30 sessions on five days a week, over four to six weeks. In depression, studies show that the effect grows with the number of sessions; fewer than twenty are often not enough. Accelerated protocols with several sessions a day shorten the series to about five days. How many you need is set after the assessment and adjusted as the course unfolds.
How long does rTMS last?
In depression, improvements after a full series persist for several months in many patients in studies; some later need maintenance sessions or a second series. How long the effect carries depends on diagnosis, concurrent treatment and life circumstances. That is why we repeat the questionnaires after the series, add a qEEG where needed, and discuss with you whether and when booster sessions make sense.
Is rTMS painful?
rTMS is generally not painful. You feel a rhythmic tapping on the scalp and hear the coil click; some people find the first sessions uncomfortable, and that usually eases after a few appointments. No anaesthesia is needed, and you stay awake and responsive. Details in our article Is rTMS painful?
What are the side effects of rTMS?
Most common are a temporary headache, a tender scalp or mild tiredness right after the session. Very rarely a seizure can be triggered, which is why we screen for contraindications such as epilepsy or metal in the head beforehand. Systemic side effects familiar from medication (weight, libido, sedation) do not occur. You can carry on with your day after every session.
Does health insurance pay for rTMS?
German statutory health insurers do not routinely cover outpatient rTMS; reimbursement is possible only through an individual application. Private insurers often reimburse in full or in part, depending on the policy. We treat self-paying and privately insured patients and provide findings and a cost plan for your application. In detail: TMS therapy cost & insurance.
rTMS or ECT – what is the difference?
Electroconvulsive therapy (ECT) induces a controlled seizure under general anaesthesia and is considered particularly effective in the most severe depressions, including psychotic ones. rTMS works without anaesthesia, without a seizure and without memory side effects, and has weaker evidence in very severe courses. For many people with treatment-resistant depression, rTMS is the gentler first step; ECT remains an option when other routes are not enough.
Does rTMS help with anxiety?
The evidence in anxiety disorders is growing but weaker than in depression. Meta-analyses show moderate effects, especially in generalised anxiety and when anxiety occurs together with depression. For anxiety we often combine rTMS with neurofeedback or taVNS and use it when the assessment supports it. More: Anxiety disorders.
Where can I get rTMS near me?
The Douwes Brain Center is in Bad Aibling, Upper Bavaria, about 50 minutes from Munich and 20 minutes from Rosenheim via the A8, with a railway station in town. Treatment is outpatient; for accelerated 5-day protocols there are hotels within walking distance. All travel and stay details: TMS therapy near Munich.
Who should not have rTMS?
rTMS is not suitable with ferromagnetic metal in the head (such as clips, shrapnel or a cochlear implant). With implanted electronic devices, epilepsy, pregnancy, acute severe illness or medication that lowers the seizure threshold, Dr. med. univ. Julian Douwes decides after an individual review. A dental implant or glasses are not an obstacle. The full check takes place in the first consultation.

rTMS for depression is backed by randomised trials, meta-analyses and guidelines, and still not everyone responds the same way. Your protocol follows your findings, and we measure the course instead of waiting out thirty sessions.

Part of Clinicum St. Georg, under the medical direction of Dr. med. univ. Julian Douwes. Outpatient, evidence-graded, tailored to your profile. More on our program.

rTMS (Repetitive Transcranial Magnetic Stimulation): is it right for you?

The assessment decides, not a brochure. We clarify it in a free consultation, with no obligation and full confidentiality.

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